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KMID : 0366919980100010230
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Sungkyun Pharmceutical Journal
1998 Volume.10 No. 1 p.230 ~ p.233
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Acute Subcutaneous Toxicity of DWP-311 in Rats
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Abstract
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The acute toxicity of DWP-311 was investigated in Sprague-Dawley rats. DWP-311 was subcutaneously administratered at dose levels of 595, 1,070, 1,930, 3,470, and 6,250 ㎎/㎏. In this study, we daily examined numbers of deaths, clinical signs, body weights, and pathological examinations for 7 days after administration of DWP-311. The results indicate that DWP-311 did not show any toxic effect in rats and the oral LD_50 value was over 6,250 ㎎/㎏ in Sprague-Dawley rats.
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